C14orf142 (GON7) Human Gene Knockout Kit (CRISPR)
CAT#: KN206178BN
C14orf142 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | C14orf142 |
Locus ID | 84520 |
Components |
KN206178G1, C14orf142 gRNA vector 1 in pCas-Guide CRISPR vector KN206178G2, C14orf142 gRNA vector 2 in pCas-Guide CRISPR vector KN206178BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_032490 |
UniProt ID | Q9BXV9 |
Synonyms | PNAS-127 |
Summary | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit OSGEP in the complex.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
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Resources
Other Versions
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KN206178 | GON7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN206178LP | C14orf142 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN206178RB | C14orf142 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN406178 | GON7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA113579 | GON7 CRISPRa kit - CRISPR gene activation of human GON7 subunit of KEOPS complex |
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