C11orf17 (AKIP1) Human Gene Knockout Kit (CRISPR)

CAT#: KN205929RB

AKIP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: C11orf17
• Locus ID: 56672
• Components:

  KN205929G1, C11orf17 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205929G2, C11orf17 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205929RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001206645, NM_001206646, NM_001206647, NM_001206648, NM_020642, NM_182901, NR_045417, NR_045418
• UniProt ID: Q9NQ31
• Synonyms: BCA3; C11orf17
• Summary: This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]