Hsp75 (TRAP1) Human Gene Knockout Kit (CRISPR)

CAT#: KN203439LP

TRAP1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: Hsp75
• Locus ID: 10131
• Components:

  KN203439G1, Hsp75 gRNA vector 1 in pCas-Guide CRISPR vector

  KN203439G2, Hsp75 gRNA vector 2 in pCas-Guide CRISPR vector

  KN203439LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001272049, NM_016292
• UniProt ID: Q12931
• Synonyms: HSP 75; HSP75; HSP90L; TRAP-1
• Summary: This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]