RTN4IP1 Human Gene Knockout Kit (CRISPR)
CAT#: KN202957BN
RTN4IP1 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
USD 450.00
USD 457.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | RTN4IP1 |
Locus ID | 84816 |
Components |
KN202957G1, RTN4IP1 gRNA vector 1 in pCas-Guide CRISPR vector KN202957G2, RTN4IP1 gRNA vector 2 in pCas-Guide CRISPR vector KN202957BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001318746, NM_032730 |
UniProt ID | Q8WWV3 |
Synonyms | NIMP; OPA10 |
Summary | This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
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KN202957 | RTN4IP1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN202957LP | RTN4IP1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN202957RB | RTN4IP1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN402957 | RTN4IP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA113704 | RTN4IP1 CRISPRa kit - CRISPR gene activation of human reticulon 4 interacting protein 1 |
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