CD71 (TFRC) Human Gene Knockout Kit (CRISPR)

CAT#: KN200980RB

TFRC - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: CD71
• Locus ID: 7037
• Components:

  KN200980G1, CD71 gRNA vector 1 in pCas-Guide CRISPR vector

  KN200980G2, CD71 gRNA vector 2 in pCas-Guide CRISPR vector

  KN200980RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001128148, NM_001313965, NM_001313966, NM_003234
• UniProt ID: P02786
• Synonyms: CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR
• Summary: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]