GSK3 beta (GSK3B) Human Gene Knockout Kit (CRISPR)
CAT#: KN200468LP
GSK3B - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | GSK3 beta |
Locus ID | 2932 |
Components |
KN200468G1, GSK3 beta gRNA vector 1 in pCas-Guide CRISPR vector KN200468G2, GSK3 beta gRNA vector 2 in pCas-Guide CRISPR vector KN200468LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001146156, NM_002093, NM_001354596 |
UniProt ID | P49841 |
Synonyms | glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform |
Summary | The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017] |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN200468 | GSK3B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN200468BN | GSK3B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN200468RB | GSK3B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN400468 | GSK3B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA101983 | GSK3B CRISPRa kit - CRISPR gene activation of human glycogen synthase kinase 3 beta |
USD 1,657.00 |
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