Mouse Flrt1 activation kit by CRISPRa

CAT#: GA217351

Flrt1 CRISPRa kit - CRISPR gene activation of mouse fibronectin leucine rich transmembrane protein 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Flrt1
• Locus ID: 396184
• Kit Components:

  GA217351G1, Flrt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA217351G2, Flrt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA217351G3, Flrt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_201411
• UniProt ID: Q6RKD8
• Synonyms: AW742165; D630040I23Rik
• Summary: Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases (PubMed:16872596, PubMed:20421966). Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length (PubMed:20421966). May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3 (PubMed:22405201).[UniProtKB/Swiss-Prot Function]