Mouse Adgrg5 activation kit by CRISPRa

CAT#: GA217210

Adgrg5 CRISPRa kit - CRISPR gene activation of mouse adhesion G protein-coupled receptor G5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Adgrg5
• Locus ID: 382045
• Kit Components:

  GA217210G1, Adgrg5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA217210G2, Adgrg5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA217210G3, Adgrg5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033468, NM_001145972
• UniProt ID: Q3V3Z3
• Synonyms: Gm1109; Gpr114; PGR27
• Summary: Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway (PubMed:22575658). Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking) (PubMed:26499266).[UniProtKB/Swiss-Prot Function]