Mouse Adgrl1 activation kit by CRISPRa

CAT#: GA216850

Adgrl1 CRISPRa kit - CRISPR gene activation of mouse adhesion G protein-coupled receptor L1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Adgrl1
• Locus ID: 330814
• Kit Components:

  GA216850G1, Adgrl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA216850G2, Adgrl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA216850G3, Adgrl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181039
• UniProt ID: Q80TR1
• Synonyms: 2900070I05Rik; AI182398; CLIBA; Lec2; Lphn1; mKIAA0821
• Summary: Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity).[UniProtKB/Swiss-Prot Function]