Mouse Med13 activation kit by CRISPRa

CAT#: GA216636

Med13 CRISPRa kit - CRISPR gene activation of mouse mediator complex subunit 13

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Med13
• Locus ID: 327987
• Kit Components:

  GA216636G1, Med13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA216636G2, Med13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA216636G3, Med13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080931
• UniProt ID: Q5SWW4
• Synonyms: 1110067M05Rik; D030023K18; Thrap1; Trap240
• Summary: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).[UniProtKB/Swiss-Prot Function]