Mouse Ric3 activation kit by CRISPRa

CAT#: GA216479

Ric3 CRISPRa kit - CRISPR gene activation of mouse RIC3 acetylcholine receptor chaperone

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ric3
• Locus ID: 320360
• Kit Components:

  GA216479G1, Ric3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA216479G2, Ric3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA216479G3, Ric3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001038624, NM_001311161, NM_178780
• UniProt ID: Q8BPM6
• Synonyms: E130307J04Rik
• Summary: Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.[UniProtKB/Swiss-Prot Function]