Mouse Agxt2 activation kit by CRISPRa

CAT#: GA215954

Agxt2 CRISPRa kit - CRISPR gene activation of mouse alanine-glyoxylate aminotransferase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Agxt2
• Locus ID: 268782
• Kit Components:

  GA215954G1, Agxt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215954G2, Agxt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215954G3, Agxt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031851, NM_001310735, NM_001310736
• Synonyms: AI303810; AI663818
• Summary: Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.[UniProtKB/Swiss-Prot Function]