Mouse Prok1 activation kit by CRISPRa

CAT#: GA215344

Prok1 CRISPRa kit - CRISPR gene activation of mouse prokineticin 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Prok1
• Locus ID: 246691
• Kit Components:

  GA215344G1, Prok1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215344G2, Prok1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215344G3, Prok1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001044382, NM_001357885
• UniProt ID: Q14A28
• Synonyms: EG-VEGF
• Summary: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.[UniProtKB/Swiss-Prot Function]