Mouse Rgs9bp activation kit by CRISPRa

CAT#: GA215164

Rgs9bp CRISPRa kit - CRISPR gene activation of mouse regulator of G-protein signalling 9 binding protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Rgs9bp
• Locus ID: 243923
• Kit Components:

  GA215164G1, Rgs9bp gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA215164G2, Rgs9bp gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA215164G3, Rgs9bp gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145840
• UniProt ID: Q148R9
• Synonyms: R9AP; Rgs9-1bp
• Summary: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation.[UniProtKB/Swiss-Prot Function]