Mouse Gp6 activation kit by CRISPRa
CAT#: GA215149
Gp6 CRISPRa kit - CRISPR gene activation of mouse glycoprotein 6 (platelet)
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Gp6 |
Locus ID | 243816 |
Kit Components | GA215149G1, Gp6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215149G2, Gp6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215149G3, Gp6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001163014 |
UniProt ID | P0C191 |
Synonyms | 9830166G18Rik; Gm469; Gpvi |
Summary | Collagen receptor involved in collagen-induced platelet adhesion and activation (PubMed:16139873, PubMed:24368846). Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN507136 | Gp6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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