Mouse Carf activation kit by CRISPRa

CAT#: GA214968

Carf CRISPRa kit - CRISPR gene activation of mouse calcium response factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Carf
• Locus ID: 241066
• Kit Components:

  GA214968G1, Carf gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA214968G2, Carf gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA214968G3, Carf gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285463, NM_001285473, NM_139150, NR_104344
• UniProt ID: Q8VHI4
• Synonyms: Als2cr8; ECBRC-FC1; ECBRC-FC2
• Summary: Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence (By similarity).[UniProtKB/Swiss-Prot Function]