Mouse Fhdc1 activation kit by CRISPRa

CAT#: GA214073

Fhdc1 CRISPRa kit - CRISPR gene activation of mouse FH2 domain containing 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Fhdc1
• Locus ID: 229474
• Kit Components:

  GA214073G1, Fhdc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA214073G2, Fhdc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA214073G3, Fhdc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033301, NM_001205355
• UniProt ID: Q3ULZ2
• Synonyms: 6330505N24Rik; Gm126
• Summary: Microtubule-associated formin which regulates both actin and microtubule dynamics. Induces microtubule acetylation and stabilization and actin stress fiber formation (PubMed:18815276). Regulates Golgi ribbon formation (PubMed:26564798). Required for normal cilia assembly. Early in cilia assembly, may assist in the maturation and positioning of the centrosome/basal body, and once cilia assembly has initiated, may also promote cilia elongation by inhibiting disassembly (PubMed:29742020).[UniProtKB/Swiss-Prot Function]