Mouse Arhgap29 activation kit by CRISPRa

CAT#: GA213195

Arhgap29 CRISPRa kit - CRISPR gene activation of mouse Rho GTPase activating protein 29

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Arhgap29
• Locus ID: 214137
• Kit Components:

  GA213195G1, Arhgap29 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213195G2, Arhgap29 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213195G3, Arhgap29 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_172525, NM_001356524
• UniProt ID: Q8CGF1
• Synonyms: 6720461J18Rik; A830014I19; AU040217; B130017I01Rik; C76601; Parg1
• Summary: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho (By similarity). In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.[UniProtKB/Swiss-Prot Function]