Mouse Cacng5 activation kit by CRISPRa

CAT#: GA212529

Cacng5 CRISPRa kit - CRISPR gene activation of mouse calcium channel, voltage-dependent, gamma subunit 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cacng5
• Locus ID: 140723
• Kit Components:

  GA212529G1, Cacng5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212529G2, Cacng5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212529G3, Cacng5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199301, NM_080644
• UniProt ID: Q8VHW4
• Summary: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).[UniProtKB/Swiss-Prot Function]