Mouse Grik4 activation kit by CRISPRa

CAT#: GA212333

Grik4 CRISPRa kit - CRISPR gene activation of mouse glutamate receptor, ionotropic, kainate 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Grik4
• Locus ID: 110637
• Kit Components:

  GA212333G1, Grik4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212333G2, Grik4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212333G3, Grik4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_175481
• UniProt ID: Q8BMF5
• Synonyms: 6330551K01Rik; GluK4; GluRgamma1; KA-1; KA1
• Summary: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > glutamate >> AMPA (By similarity).[UniProtKB/Swiss-Prot Function]