Mouse Magee1 activation kit by CRISPRa

CAT#: GA212006

Magee1 CRISPRa kit - CRISPR gene activation of mouse melanoma antigen, family E, 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Magee1
• Locus ID: 107528
• Kit Components:

  GA212006G1, Magee1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212006G2, Magee1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212006G3, Magee1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_053201
• UniProt ID: Q6PCZ4
• Synonyms: AI847422; DAMAGE; mMage-e1
• Summary: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (By similarity).[UniProtKB/Swiss-Prot Function]