Mouse Qtrt2 activation kit by CRISPRa

CAT#: GA211921

Qtrt2 CRISPRa kit - CRISPR gene activation of mouse queuine tRNA-ribosyltransferase accessory subunit 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Qtrt2
• Locus ID: 106248
• Kit Components:

  GA211921G1, Qtrt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211921G2, Qtrt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211921G3, Qtrt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_029128, NM_001356328, NM_001356329
• UniProt ID: B8ZXI1
• Synonyms: 3110012M05Rik; 4930470H18Rik; AI648807; Qtrt2
• Summary: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[UniProtKB/Swiss-Prot Function]