Mouse Amigo2 activation kit by CRISPRa

CAT#: GA211895

Amigo2 CRISPRa kit - CRISPR gene activation of mouse adhesion molecule with Ig like domain 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Amigo2
• Locus ID: 105827
• Kit Components:

  GA211895G1, Amigo2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211895G2, Amigo2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211895G3, Amigo2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164563, NM_001164602, NM_178114
• UniProt ID: Q80ZD9
• Synonyms: AI415330; Ali1; AMIGO-2; AW208913
• Summary: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain (By similarity).[UniProtKB/Swiss-Prot Function]