Mouse H3c8 activation kit by CRISPRa

CAT#: GA211490

Hist1h3g CRISPRa kit - CRISPR gene activation of mouse histone cluster 1, H3g

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: H3c8
• Locus ID: 97908
• Kit Components:

  GA211490G1, H3c8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211490G2, H3c8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211490G3, H3c8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145073
• UniProt ID: P68433
• Synonyms: H3.1-221; M32460
• Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]