Mouse Srd5a2 activation kit by CRISPRa

CAT#: GA211436

Srd5a2 CRISPRa kit - CRISPR gene activation of mouse steroid 5 alpha-reductase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Srd5a2
• Locus ID: 94224
• Kit Components:

  GA211436G1, Srd5a2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211436G2, Srd5a2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211436G3, Srd5a2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_053188
• UniProt ID: Q99N99
• Synonyms: 5ART2; S5AR 2
• Summary: Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.[UniProtKB/Swiss-Prot Function]