Mouse Mepe activation kit by CRISPRa

CAT#: GA211412

Mepe CRISPRa kit - CRISPR gene activation of mouse matrix extracellular phosphoglycoprotein with ASARM motif (bone)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Mepe
• Locus ID: 94111
• Kit Components:

  GA211412G1, Mepe gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211412G2, Mepe gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211412G3, Mepe gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_053172
• UniProt ID: Q8K4L6
• Synonyms: Of45
• Summary: Regulates renal phosphate and uric acid excretion (PubMed:26051469). Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes (PubMed:11414762, PubMed:12421822, PubMed:15843468, PubMed:22766095). Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (PubMed:26927967). Increases dental pulp stem cell proliferation (By similarity).[UniProtKB/Swiss-Prot Function]