Mouse Trim7 activation kit by CRISPRa

CAT#: GA211405

Trim7 CRISPRa kit - CRISPR gene activation of mouse tripartite motif-containing 7

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Trim7
• Locus ID: 94089
• Kit Components:

  GA211405G1, Trim7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211405G2, Trim7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211405G3, Trim7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001347446, NM_053166, NM_001347436
• UniProt ID: Q923T7
• Synonyms: AI790312
• Summary: E3 ubiquitin-protein ligase (By similarity). Mediates 'Lys-63'-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation (By similarity).[UniProtKB/Swiss-Prot Function]