Mouse Dcp1a activation kit by CRISPRa

CAT#: GA210395

Dcp1a CRISPRa kit - CRISPR gene activation of mouse decapping mRNA 1A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Dcp1a
• Locus ID: 75901
• Kit Components:

  GA210395G1, Dcp1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210395G2, Dcp1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210395G3, Dcp1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133761
• UniProt ID: Q91YD3
• Synonyms: 1110066A22Rik; 4930568L04Rik; AU019772; D14Ertd817e; Mitc1; SMIF
• Summary: Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1 (By similarity).[UniProtKB/Swiss-Prot Function]