Mouse Tex19.2 activation kit by CRISPRa

CAT#: GA208677

Tex19.2 CRISPRa kit - CRISPR gene activation of mouse testis expressed gene 19.2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Tex19.2
• Locus ID: 70956
• Kit Components:

  GA208677G1, Tex19.2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208677G2, Tex19.2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208677G3, Tex19.2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_027622
• UniProt ID: Q9D5S1
• Synonyms: 4921530G04Rik; Tex19b
• Summary: May be required during spermatogenesis, probably by participating in the repression of retrotransposable elements and prevent their mobilization (Probable). With its paralog, Tex19.1, collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:28254886).[UniProtKB/Swiss-Prot Function]