Mouse Arhgap45 activation kit by CRISPRa

CAT#: GA208602

Arhgap45 CRISPRa kit - CRISPR gene activation of mouse Rho GTPase activating protein 45

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Arhgap45
• Locus ID: 70719
• Kit Components:

  GA208602G1, Arhgap45 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208602G2, Arhgap45 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208602G3, Arhgap45 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142701, NM_001347074, NM_027521
• UniProt ID: Q3TBD2
• Synonyms: 6330406L22Rik; AW539505; Ha-1
• Summary: Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.[UniProtKB/Swiss-Prot Function]