Mouse Pdlim7 activation kit by CRISPRa

CAT#: GA207308

Pdlim7 CRISPRa kit - CRISPR gene activation of mouse PDZ and LIM domain 7

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Pdlim7
• Locus ID: 67399
• Kit Components:

  GA207308G1, Pdlim7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA207308G2, Pdlim7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA207308G3, Pdlim7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114087, NM_001114088, NM_026131, NR_104287
• UniProt ID: Q3TJD7
• Synonyms: LMP
• Summary: May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]