Mouse Crls1 activation kit by CRISPRa

CAT#: GA206851

Crls1 CRISPRa kit - CRISPR gene activation of mouse cardiolipin synthase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Crls1
• Locus ID: 66586
• Kit Components:

  GA206851G1, Crls1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206851G2, Crls1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206851G3, Crls1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024385, NM_025646, NM_001024384
• UniProt ID: Q80ZM8
• Synonyms: 0610009I22Rik; 4930557M15Rik; 5730490M08Rik
• Summary: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.[UniProtKB/Swiss-Prot Function]