Mouse Sf3b5 activation kit by CRISPRa
CAT#: GA206591
Sf3b5 CRISPRa kit - CRISPR gene activation of mouse splicing factor 3b, subunit 5
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Sf3b5 |
Locus ID | 66125 |
Kit Components | GA206591G1, Sf3b5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206591G2, Sf3b5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206591G3, Sf3b5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_175102 |
UniProt ID | Q923D4 |
Synonyms | 10kDa; 1110005L13Rik; AU043053; Sf3b10 |
Summary | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN515646 | Sf3b5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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