Mouse Sumf1 activation kit by CRISPRa

CAT#: GA206315

Sumf1 CRISPRa kit - CRISPR gene activation of mouse sulfatase modifying factor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Sumf1
• Locus ID: 58911
• Kit Components:

  GA206315G1, Sumf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206315G2, Sumf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206315G3, Sumf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145937
• UniProt ID: Q8R0F3
• Synonyms: AA543204; AI463102; AI851573; FGE
• Summary: Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.[UniProtKB/Swiss-Prot Function]