Mouse Cysltr1 activation kit by CRISPRa

CAT#: GA206306

Cysltr1 CRISPRa kit - CRISPR gene activation of mouse cysteinyl leukotriene receptor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cysltr1
• Locus ID: 58861
• Kit Components:

  GA206306G1, Cysltr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206306G2, Cysltr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206306G3, Cysltr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281859, NM_001281862, NM_021476
• UniProt ID: Q99JA4
• Synonyms: BB147369; Cyslt1; CysLT1R
• Summary: Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.[UniProtKB/Swiss-Prot Function]