Mouse Cdc42se1 activation kit by CRISPRa

CAT#: GA206241

Cdc42se1 CRISPRa kit - CRISPR gene activation of mouse CDC42 small effector 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Cdc42se1
• Locus ID: 57912
• Kit Components:

  GA206241G1, Cdc42se1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206241G2, Cdc42se1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206241G3, Cdc42se1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001038708, NM_172395
• UniProt ID: Q8BHL7
• Synonyms: 1300002M12Rik; AW558204; Cdcse1; SCIP1; Spec1
• Summary: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity).[UniProtKB/Swiss-Prot Function]