Mouse Defb4 activation kit by CRISPRa

CAT#: GA206016

Defb4 CRISPRa kit - CRISPR gene activation of mouse defensin beta 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Defb4
• Locus ID: 56519
• Kit Components:

  GA206016G1, Defb4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA206016G2, Defb4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA206016G3, Defb4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019728
• UniProt ID: P82019
• Synonyms: 2310001F05Rik; BD-4
• Summary: Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).[UniProtKB/Swiss-Prot Function]