Mouse Plpp2 activation kit by CRISPRa

CAT#: GA205364

Plpp2 CRISPRa kit - CRISPR gene activation of mouse phospholipid phosphatase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Plpp2
• Locus ID: 50784
• Kit Components:

  GA205364G1, Plpp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205364G2, Plpp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205364G3, Plpp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302389, NM_001302390, NM_001302442, NM_015817
• UniProt ID: Q9DAX2
• Synonyms: Lpp2; PAP2-G; PAP2-gamma; PAP2c; Ppap2c
• Summary: The protein encoded by this gene is a lipid phosphate phosphohydrolase. It is an integral membrane protein that catalyzes the conversion of phosphatidic acid to diacylglycerol and inorganic phosphate. The transcript is expressed at high levels in lung, liver, and kidney and at low levels in brain and heart. Null mutant mice are viable and fertile and display no overt phenotypic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]