Mouse Fbxo17 activation kit by CRISPRa

CAT#: GA205344

Fbxo17 CRISPRa kit - CRISPR gene activation of mouse F-box protein 17

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Fbxo17
• Locus ID: 50760
• Kit Components:

  GA205344G1, Fbxo17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205344G2, Fbxo17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205344G3, Fbxo17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001310687, NM_015796
• UniProt ID: Q9QZM8
• Synonyms: Fbg4; Fbx17; Fbxo26
• Summary: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity).[UniProtKB/Swiss-Prot Function]