Mouse Dysf activation kit by CRISPRa

CAT#: GA205029

Dysf CRISPRa kit - CRISPR gene activation of mouse dysferlin

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Dysf
• Locus ID: 26903
• Kit Components:

  GA205029G1, Dysf gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA205029G2, Dysf gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA205029G3, Dysf gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077694, NM_001310152, NM_021469
• UniProt ID: Q9ESD7
• Synonyms: 2310004N10Rik; AI604795; D6Pas3
• Summary: Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.[UniProtKB/Swiss-Prot Function]