Mouse Vax2 activation kit by CRISPRa

CAT#: GA204905

Vax2 CRISPRa kit - CRISPR gene activation of mouse ventral anterior homeobox 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Vax2
• Locus ID: 24113
• Kit Components:

  GA204905G1, Vax2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204905G2, Vax2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204905G3, Vax2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011912
• UniProt ID: Q9WTP9
• Synonyms: Dres93
• Summary: Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina.[UniProtKB/Swiss-Prot Function]