Mouse Tcf7l1 activation kit by CRISPRa

CAT#: GA204241

Tcf7l1 CRISPRa kit - CRISPR gene activation of mouse transcription factor 7 like 1 (T cell specific, HMG box)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Tcf7l1
• Locus ID: 21415
• Kit Components:

  GA204241G1, Tcf7l1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204241G2, Tcf7l1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204241G3, Tcf7l1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079822, NM_009332
• UniProt ID: Q9Z1J1
• Synonyms: bHLHb21; Tcf-3; Tcf3
• Summary: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis.[UniProtKB/Swiss-Prot Function]