Mouse Stat5b activation kit by CRISPRa

CAT#: GA204127

Stat5b CRISPRa kit - CRISPR gene activation of mouse signal transducer and activator of transcription 5B

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Stat5b
• Locus ID: 20851
• Kit Components:

  GA204127G1, Stat5b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204127G2, Stat5b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204127G3, Stat5b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113563, NM_011489, NM_001362682
• UniProt ID: P42232
• Summary: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.[UniProtKB/Swiss-Prot Function]