Mouse Slc2a4 activation kit by CRISPRa

CAT#: GA203954

Slc2a4 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 2 (facilitated glucose transporter), member 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Slc2a4
• Locus ID: 20528
• Kit Components:

  GA203954G1, Slc2a4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203954G2, Slc2a4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203954G3, Slc2a4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009204, NM_001359114
• UniProt ID: P14142
• Synonyms: Glut-4; Glut4
• Summary: Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation (PubMed:26240143, PubMed:26629404). Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells (PubMed:26240143, PubMed:26629404). Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell (PubMed:26240143, PubMed:26629404).[UniProtKB/Swiss-Prot Function]