Mouse Recql activation kit by CRISPRa

CAT#: GA203603

Recql CRISPRa kit - CRISPR gene activation of mouse RecQ protein-like

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Recql
• Locus ID: 19691
• Kit Components:

  GA203603G1, Recql gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203603G2, Recql gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203603G3, Recql gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204906, NM_001204907, NM_023042, NM_001355511
• UniProt ID: Q9Z129
• Synonyms: RecQ1
• Summary: Isoform alpha is a DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Isoform beta may have important roles in the meiotic process. Both isoforms exhibit a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.[UniProtKB/Swiss-Prot Function]