Mouse Rad23a activation kit by CRISPRa

CAT#: GA203548

Rad23a CRISPRa kit - CRISPR gene activation of mouse RAD23 homolog A, nucleotide excision repair protein

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Rad23a
• Locus ID: 19358
• Kit Components:

  GA203548G1, Rad23a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203548G2, Rad23a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203548G3, Rad23a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001297606, NM_001297607, NM_009010
• UniProt ID: P54726
• Synonyms: 2310040P19Rik; AL024030; HR23A; mHR23A
• Summary: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome (By similarity).[UniProtKB/Swiss-Prot Function]