Mouse Minpp1 activation kit by CRISPRa

CAT#: GA202658

Minpp1 CRISPRa kit - CRISPR gene activation of mouse multiple inositol polyphosphate histidine phosphatase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Minpp1
• Locus ID: 17330
• Kit Components:

  GA202658G1, Minpp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202658G2, Minpp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202658G3, Minpp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010799
• UniProt ID: Q9Z2L6
• Synonyms: AA408516
• Summary: Acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate (By similarity). Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity).[UniProtKB/Swiss-Prot Function]