Mouse Ldb1 activation kit by CRISPRa

CAT#: GA202429

Ldb1 CRISPRa kit - CRISPR gene activation of mouse LIM domain binding 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Ldb1
• Locus ID: 16825
• Kit Components:

  GA202429G1, Ldb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202429G2, Ldb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202429G3, Ldb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113408, NM_010697, NM_001360336
• UniProt ID: P70662
• Synonyms: CLIM2; NLI
• Summary: Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.[UniProtKB/Swiss-Prot Function]