Mouse Klk1b27 activation kit by CRISPRa

CAT#: GA202337

Klk1b27 CRISPRa kit - CRISPR gene activation of mouse kallikrein 1-related peptidase b27

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Klk1b27
• Locus ID: 16619
• Kit Components:

  GA202337G1, Klk1b27 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202337G2, Klk1b27 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202337G3, Klk1b27 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020268
• UniProt ID: Q9JM71
• Synonyms: Gk27; Klk21l; Klk27; mGK-27
• Summary: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016]