Mouse Folr1 activation kit by CRISPRa
CAT#: GA201461
Folr1 CRISPRa kit - CRISPR gene activation of mouse folate receptor 1 (adult)
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Folr1 |
Locus ID | 14275 |
Kit Components | GA201461G1, Folr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201461G2, Folr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201461G3, Folr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001252552, NM_001252553, NM_001252554, NM_008034 |
UniProt ID | P35846 |
Synonyms | FBP1; Folbp-1; Folbp1 |
Summary | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.[UniProtKB/Swiss-Prot Function] |
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Other Versions
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KN306057 | Folr1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN306057BN | Folr1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN306057LP | Folr1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN306057RB | Folr1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN506057 | Folr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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